*Updated 18 Feb 2016* As I progress further and further into my reading and research on MTHFR and related conditions, glutathione (GSH) keeps popping up. Having reduced levels of glutathione is associated with many diseases and health conditions, including cancer, cystic fibrosis, Parkinson’s disease, Alzheimer’s disease, hypertension, atherosclerosis, emphysema, asthma, ME/chronic fatigue syndrome, fibromyalgia, autism, bipolar disorder and multiple sclerosis. In fact, if I hold up a list of diseases associated with reduced glutathione next to a list of diseases associated with MTHFR,… Read more »

Many people will experience extended periods of fatigue during the course of their lives. Myalgic Encephalomyelitis (ME) and Chronic Fatigue Syndrome (CFS), however, involve more than just chronic tiredness and can strike both children and adults. In order to be diagnosed, a patient must meet all seven strict criteria (fatigue, post-exertional malaise, fatigue or pain, sleep dysfunction, pain, neurological/cognitive problems and two of the following: autonomic manifestations, neuroendocrine manifestations and immune manifestations). It is estimated that 2.5 to 5 per… Read more »

*Updated on 5 Feb, 2014* Gather together some MTHFR patients and start talking about what ails them. There’s a laundry list of associated illnesses for people with methylation defects and those illnesses do present among MTHFR patients. Autism, cancer, heart disease, fibromyalgia, infertility and recurrent miscarriages, Parkinson’s disease, polycystic ovarian syndrome and stroke are just a few of the chronic conditions where MTHFR gene mutations have been identified as a contributing factor. So any doctor who tells you that MTHFR isn’t… Read more »